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Scientific foundations

Scientific foundations and responsible interpretation

Methodology, sequencing framework, reference context, scoring and confidence — explained in clear, educational language.

From sample to interpretation

Every report follows the same transparent pathway

01 →

Sample

A collected sample is submitted and logged for processing.

02 →

Sequencing

The chosen method (16S, WGS or MetaT) measures microbial signal at its supported depth.

03 →

Bioinformatics

Reads are processed against curated references with quality control at each step.

04

Interpretation

ATLAS organises features into scores, panels and confidence cues — never a diagnosis.

Light-microscope view of a microbial colony margin, with branching filaments and droplet structures spreading across the field.

Under the microscope

The subject of every score is a living community

Before any sequencing read or reference comparison, there is biology like this — filaments, margins and micro-structures growing together. The frameworks below exist to describe that reality carefully, within the limits of measurement.

Light-microscope view of a microbial colony margin, with branching filaments and droplet structures spreading across the field. Photo: Korinna, Wikimedia Commons, CC BY 4.0.

Structure first

A community, read as structure

Every score begins as ecology: organisms of different relative abundance co-occurring in one community. The science below describes how that structure is measured, compared with reference context, and interpreted — always within the limits of the chosen method.

Conceptual community map: each circle is an organism, circle size suggests relative abundance, and hairlines suggest co-occurrence. Illustrative — not measured data.

Explore the science

Six topics behind every result

How we describe results

Four principles applied to every interpretation

01

Describe, don’t diagnose

We report microbial composition and ecological context — not disease.

02

Show the confidence

Every output carries a visible method-support and confidence cue.

03

Respect the method ceiling

Claims never exceed what the chosen sequencing method can resolve.

04

Compare with context

Reference comparisons are framed with their limits, not as verdicts.

All science content is educational. It explains sequencing-derived microbial patterns and reference-context comparison — not diagnosis or medical advice.

See the science applied on a real report

Configure a test to choose your ecosystem, sequencing depth and report level. Method scope and limitations are shown throughout.

Configure a test Explore ATLAS™